As civilizations progress, eventually distance and maybe even time becomes less of a problem.
We have absolutely no idea what the travel capabilities would be for a civilization that has been around 1000 + yrs longer than we have. For some reason people seem to forget that when discussing possible UFOs, its almost comical to think distance would be the same problem to them as it is for us right now. LOL
I believe the universe is probably like Star Wars/ Star Trek, LOTS and LOTS of different systems out there, LOTS of different types of life, some very intelligent, others, not so much. Some probably are aware of each other, any may even have trade set up with each other, we just have no way of knowing anything about this, but whatever is out there, the same God we worship, created it ALL.