It can be taken in all the ways of the senses of Scripture, literal and spiritual. The spiritual senses include: the allegorical (or “typological” sense), the moral (or “tropological” sense), and the anagogical (or “heavenly”) sense.
source
Good answer. They were real healings and they had a spiritual significance.
We have three basic ways of knowing God. We instinctively know he is God, though we don’t understand all the details. You read the Word, or experience something and know God was there. This is hearing. Like sheep hearing the shepherd’s voice but not understanding the words. Jesus healed the deaf.
We know God intellectually by using the faculties of the mind and reading his word. This is seeing. Jesus healed the blind.
We live with Christ within. This is walking. Jesus healed the lame.
Leprosy represents sin. Jesus fulfills the law of the leper. He became a leper by being made to be sin. He ‘shaved his head’ when the Father departed from him and he lost his authority. He covered his lip when he prayed ‘remove this cup’ and didn’t get an answer. When he was totally covered with our sin he was declared clean in the resurrection. As the leper would then go through a ceremony like the ordination of a priest, Jesus became our high priest.
The dead represent those who are dead in trespass and sin, given a new life in Christ.
The poor represent those with nothing to offer God, recognizing their own sinfulness, and receiving the good news.
Mt 11:5 The blind receive their sight, and the lame walk, the lepers are cleansed, and the deaf hear, the dead are raised up, and the poor have the gospel preached to them.
Lu 7:22 Then Jesus answering said unto them, Go your way, and tell John what things ye have seen and heard; how that the blind see, the lame walk, the lepers are cleansed, the deaf hear, the dead are raised, to the poor the gospel is preached.
The metaphorical issues which are mentioned in the OP, I don’t think are interpretation, but application. When you have the things that Jesus healed taken care of, the rest falls into place.