Is this verse signifiant?

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*Genesis 3: 15 *** I will put enmity between you and the woman,and between your seed and her seed;he shall bruise your head,and you shall bruise his heel."

What does this mean?

Is it a verse of anykind of special signifiance?

Does it have a current meaning to us today?
 
The words of Genesis 3:15 are prophetic
“I will put enmities between thee and the woman, and thy seed and her seed: she shall crush thy head, and thou shalt lie in wait for her heel.”
The Catechism of the Catholic Church states that these words
are the Protoevangelium, the first gospel,
“the first announcement of the Messiah and Redeemer, and the battle between the serpent and the Woman…” (C.C.C., #410)

The Woman is Mary, the seed, Jesus. The relevance for us is that this battle continues in our daily lives as we seek to avoid temptation and sin, by the grace of God in the salvation that Jesus Son of God and Son of Mary offers us.

God bless you!
 
Here is what I wrote in my commentary
This passage in Genesis is called the Protoevangelium (“first gospel”): the first announcement of the Messiah and Redeemer, of a battle between the serpent and the Woman, and of the final victory of a descendant of hers. CCC 410
Pope John Paul II shows us how this relates to Mary and the Lord Jesus… “She (Mary) is “a woman clothed with the sun”, with the moon under her feet, and on her head a crown of stars (cf. Rev 12:1). One can say she is a Woman of cosmic scale, on a scale with the whole work of creation. At the same time she is “suffering the pangs and anguish of childbirth” (Rev 12:2) like Eve “the mother of all the living” (Gen 3:20). She also suffers because “before the woman who is about to give birth” (cf. Rev 12:4) there stands “the great dragon … that ancient serpent” (Rev 12:9), already known from the Proto-evangelium: the Evil One, the “father of lies” and of sin (cf. Jn 8:44). The “ancient serpent” wishes to devour “the child”. While we see in this text an echo of the Infancy Narrative (cf. Mt 2:13,16), we can also see that the struggle with evil and the Evil One marks the biblical exemplar of the “woman” from the beginning to the end of history. It is also a struggle for man, for his true good, for his salvation. Is not the Bible trying to tell us that it is precisely in the “woman” - Eve-Mary - that history witnesses a dramatic struggle for every human being, the struggle for his or her fundamental “yes” or “no” to God and God’s eternal plan for humanity?” John Paul II MULIERIS DIGNITATEM
The link is here litteralchristianlibrary.wetpaint.com/page/Gen.+Chapter+3
 
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