Not sure where you are going with this. Since this question is your only post with little detail I’m going to assume you are trying to imply that Mary was not ever virgin and had daughters too.
We can go into the Biblical and Historical reason why these “sister’s” are not Mary’s daughters but instead just for fun…
Let’s do the math. Listed is 4 brothers plus Jesus makes 5 and it says all sisters not both so that is atleast 3, which brings us to 8.
Since it is known that back then that at a minimum 25% of all babies died within the first year of life and 50% died by age 10, we can estimate Mary had 12 to 16 pregnancies. Wow they were gettin busy.
Now we also know from Luke 2:41-42 that only Jesus, Mary and Joseph went to the temple. So we can determine that up until the time Jesus was 12 no other brothers and sisters were born.
We also know that Jesus was around 30 in the verses in question.
So that means the other siblings must have been born in the 18 years between Luke 2 and Matthew 13.
Only Jesus and Mary were present at the wedding at Cana, so it is safe to assume that all of the other Children must have been at least 12 for Mary to leave them Home Alone
I think you see where I’m going with this…
Which seems more plausible, these brothers and sisters were cousins or Mary had 7 other children in 6 years?
Hope this helps.
God Bless