D
David_Paul
Guest
ABC (au)
09/09/05
A team of scientists in Britain have been granted official approval to create a human embryo using genetic material from two women, raising the future prospect of babies with a pair of mothers.
The group from Newcastle University in Britain has been given the green light by the Human Fertilisation and Embryology Authority (HFEA), the Government-appointed genetics and reproductive technology watchdogs for Britain, where such science is tightly regulated.
The scientists will transfer the pro-nuclei - the components of a human embryo nucleus - made by one man and woman into an unfertilised egg from another woman.
This technique is intended to help prevent mothers from passing on so-called mitochondrial diseases on to their unborn babies, genetic conditions caused by DNA outside the nucleus of a cell, in the mitochondria.
Mitochondria have their own DNA, inherited from the mother only.
If this DNA is faulty, then children can develop diseases affecting cells in the brain, heart, liver, kidney or skeletal muscles, for which there is currently no known cure.
Previous studies in mice showed in was possible to prevent the transmission of mitochondrial disease by moving the nucleus from an egg containing bad mitochondrial DNA to an unaffected egg.
Controversial research
The human trial will not see any eggs allowed to develop into babies, but the research nonetheless remains controversial.
Professor John Burn from Newcastle University stressed that the new tests would not lead to “designer babies”.
“From a philosophical or medical point of view there is no reason why we should not do this,” he said . . . .
continued here:
abc.net.au/news/newsitems/200509/s1456471.htm
09/09/05
A team of scientists in Britain have been granted official approval to create a human embryo using genetic material from two women, raising the future prospect of babies with a pair of mothers.
The group from Newcastle University in Britain has been given the green light by the Human Fertilisation and Embryology Authority (HFEA), the Government-appointed genetics and reproductive technology watchdogs for Britain, where such science is tightly regulated.
The scientists will transfer the pro-nuclei - the components of a human embryo nucleus - made by one man and woman into an unfertilised egg from another woman.
This technique is intended to help prevent mothers from passing on so-called mitochondrial diseases on to their unborn babies, genetic conditions caused by DNA outside the nucleus of a cell, in the mitochondria.
Mitochondria have their own DNA, inherited from the mother only.
If this DNA is faulty, then children can develop diseases affecting cells in the brain, heart, liver, kidney or skeletal muscles, for which there is currently no known cure.
Previous studies in mice showed in was possible to prevent the transmission of mitochondrial disease by moving the nucleus from an egg containing bad mitochondrial DNA to an unaffected egg.
Controversial research
The human trial will not see any eggs allowed to develop into babies, but the research nonetheless remains controversial.
Professor John Burn from Newcastle University stressed that the new tests would not lead to “designer babies”.
“From a philosophical or medical point of view there is no reason why we should not do this,” he said . . . .
continued here:
abc.net.au/news/newsitems/200509/s1456471.htm