During the earlier part of his life he followed the profession of an advocate at Constantinople, and was already known as a layman of considerable learning when he protested publicly (423) against the erroneous doctrine of a discourse delivered by Anastasius, the syncellus, or chaplain, of Nestorius. Shortly afterwards he again bore public witness against the Nestorian heresy as to the nature of Christ, this time during a discourse by Nestorius himself, which he interrupted with the exclamation that “the eternal Word had undergone a second generation”—i.e. of a woman, according to the flesh. Much disorder followed, but Nestorius replied with arguments against the “second generation”.