Which is worse?

[guanophore]

I would like everyone’s take on what would be the worst.

As despicable as the other two options are, the possibility exists that one might still repent and be saved. When one loses the sense of sin, one commits the unpardonable sin, because one never sees a need to repent. I have worked with those who committed the sin of murder, and those who have profaned the Sacrament (myself included) and have been able to see reconciliation.