Yes. A clear example is a baby in danger of death (Code of Canon Law, canon 891). The baby does not understand, know or agree with the Church’s morals, dogmas and doctrines. But this does not effect the validity of the sacrament of confirmation.
It happens all the time with teenagers who get confirmed “for Mom and Dad” but make a big point of how they are being tortured by the whole process, and how they don’t agree with this n’ that.
The Catholic perspective of Confirmation is that it seals and completes Baptism, when the Holy Spirit imparts the 7 gifts to strengthen the confrimands for the spiritual battle we all face in daily life as Christians. It is not supposed to be a “Come to Jesus” moment, nor is it supposed to be the person “confirming” their faith (as an alleged adult or anything else), but the bishop or priest confirming the person’s baptism.
HOWEVER, a person cannot be confirmed without professing the Faith. For an Eastern Catholic infant, the sponsors do that. For children of a certain age, they do it whether they realize it or not. For an adult from a Protestant denomination wishing to be Catholic, that adult would have to not only read but sign a profession of faith. http://www.usccb.org/catechism/text/pt2sect2chpt1art2.htm
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