We lived in Israel for three years, and have visited most of the important sites. Many Catholics enjoy visiting the sites associated with the mysteries of the Rosary. In Jerusalem you will want to visit the Church of the Holy Sepulcher, and walk the Via Dolorosa. You can attend Holy Mass in English at the Pontifical Institute of Notre Dame. You can vist the Garden of Gethsemane, and visit the Church of all Nations, a Catholic church. Look for the seal of the United States in the ceiling. Most of the sites associated with the life and ministry of the Lord are located in the Galilee region. They include Nazareth and the Church of the Annunciation, Mt. Tabor and the Church of the Transfiguration, the Mount of the Beatitudes, Tabgha and the Church of the Multiplication, and the Church of the Primacy of Peter which is right on the shore of the lake. Capernaum is beautiful with the remains of the old synagogue, and the house of St. Peter. You can renew your wedding vows at the church in Cana. If you are into the history of the crusades, you should visit Akko with it’s many crusader sites. While you up in the north go to Haife, and Mt. Carmel where you can visit the Carmelite Monastery and Elijah’s Cave. I was not able to visit Bethlehem and other West Bank sites because US government employees are not allowed to go there for security reasons. The government is being very cautious. You will be perfectly safe at any major tourist area in Israel. I am sure that I have not mentioned all of the sites that would be of interest to Catholics, but maybe another poster can suggest others.