Myth of evolution and new drug discovery

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Liquidpele, any idea why evolution threads keep being pulled or closed before we’re halfway to the thousand-post limit? It looks like someone higher up has it in for the theory. In any case, it’s been fun thrashing through the issues with you.

StAnastasia
I am not sure why they are getting pulled.
 
Believe it or not, I am looking for the truth behind all this. The current idea behind species is two groups become isolated and can no longer interbreed. However, my only issue is the idea that some novel organ could gradually appear in a macro creature. A wing on its way to becoming a wing won’t allow the macro creature to fly. A light sensitive spot has quite a ways to go before it becomes an eyeball, and stereo vision requires some precise distance between the two eyeballs to allow for full function. The function of a gill is far enough removed from the function of a lung to make any connection between the two imaginative and highly doubtful.
A halfway-formed organ can still be useful - a light-sensitive spot helps organisms find food and avoid predators, and half a wing might be able to allow gliding jumps.

At any rate, you’re using the same logical fallacy to arrive at your conclusions: The argument from ignorance.
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edwest2:
Even the experts cannot produce a bona fide transitional fossil:

See the heading:
Are there any transitional fossils?

answersingenesis.org/creation/v14/i4/fossils.asp
talkorigins.org/faqs/faq-transitional.html
talkorigins.org/faqs/comdesc/section1.html#pred4
talkorigins.org/faqs/homs/
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edwest2:
I think the next thing I want to bring up is creationism. No, not the “God did it,” let’s close up the lab and go home idea, but the idea that the earth is not billions of years old. I’m not saying it’s 6,000 years old, I’m putting forth an idea.

Right now, and this may seem surprising to the few that think the Church is perfectly OK with evolution, the Church is saying that a self-starting evolution is impossible. The textbook idea that nature does something, entirely on its own, to bring about life, is not the correct answer. God is part of the equation, a direct, causal part.

What specifically would happen, in your view, if scientists declared: The code in DNA did not appear naturally. Like a computer, which cannot program itself, DNA cannot program itself either. The Law of Probability indicates that not only is the DNA code impossible to achieve but the self-correcting aspect finalizes the idea that it could not be achieved through purely natural means.

What would happen?

Peace,
Ed
Hang on, what specifically about the law of probability indicates that DNA couldn’t be constructed through natural means?
 
Liquidpele, any idea why evolution threads keep being pulled or closed before we’re halfway to the thousand-post limit? It looks like someone higher up has it in for the theory. In any case, it’s been fun thrashing through the issues with you.

StAnastasia
I’m not sure, they’re being closed without explanation which I find a bit irritating. The last mod (Jean Anthony was it?) used to at least post why he was closing it.
 
No, I don’t, but that does not prove that they cannot under certain circumstances.
We now know that the DNA code provides the recipes for all life. The so-called junk regions are not junk. They have function.

We have to ask what came first the chicken or the egg. How would a simple multi-cellular organism come up with the complete recipe for all life?
 
I’m not sure, they’re being closed without explanation which I find a bit irritating. The last mod (Jean Anthony was it?) used to at least post why he was closing it.
It must be something you or StA are saying. 😃
 
We now know that the DNA code provides the recipes for all life. The so-called junk regions are not junk. They have function.
Well, not exactly. The research you are (probably) referring to showed that large sections of what was considered to be junk DNA may have a function. It did not demonstrate that all parts of DNA had a function.
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buffalo:
We have to ask what came first the chicken or the egg. How would a simple multi-cellular organism come up with the complete recipe for all life?
It wouldn’t. DNA isn’t an “all or nothing” thing, it doesn’t have to be present in its modern form, 100% complete, in order for an organism to survive. The idea is that the first organisms had a much, much simpler form of DNA, maybe even RNA.
 
Well, not exactly. The research you are (probably) referring to showed that large sections of what was considered to be junk DNA may have a function. It did not demonstrate that all parts of DNA had a function.

It wouldn’t. DNA isn’t an “all or nothing” thing, it doesn’t have to be present in its modern form, 100% complete, in order for an organism to survive. The idea is that the first organisms had a much, much simpler form of DNA, maybe even RNA.
The question is since DNA has an active resistance to mutations and self corrects suggests it has remained pretty much the same since the beginning.
 
DNA and the Origin of Life: Information, Specification, and Explanation

…3.2 BEYOND THE REACH OF CHANCE
Perhaps the most common popular view about the origin of life is that it happened
exclusively by chance. A few serious scientists have also voiced support for this view, at
least, at various points during their careers. In 1954 the physicist George Wald, for
example, argued for the causal efficacy of chance in conjunction vast expanses of time.
As he explained, “Time is in fact the hero of the plot. . . . Given so much time, the
impossible becomes possible, the possible probable, and the probable virtually certain”
[48; 49, p. 121]. Later in 1968 Francis Crick would suggest that the origin of the genetic
code—i.e., the translation system—might be a “frozen accident” [50, 51]. Other theories
have invoked chance as an explanation for the origin of genetic information though often
in conjunction with pre-biotic natural selection. (see below 3.3)
While outside origin-of-life biology some may still invoke ‘chance’ as an explanation
for the origin of life, most serious origin-of-life researchers now reject it as an adequate
causal explanation for the origin of biological information [52; 44, pp. 89-93; 47, p. 7].
Since molecular biologists began to appreciate the sequence specificity of proteins and
nucleic acids in the 1950s and 1960s, many calculations have been made to determine the
probability of formulating functional proteins and nucleic acids at random. Various
methods of calculating probabilities have been offered by Morowitz, Hoyle and
Wickramasinghe, Cairns-Smith, Prigogine, Yockey, and more recently, Robert Sauer [53,
pp. 5-12; 54, pp. 24-27; 55, pp. 91-96; 56; 30, pp. 246-58; 57; 34; 35; 36; 49, pp. 117-31].
For the sake of argument, these calculations have often assumed extremely favorable
prebiotic conditions (whether realistic or not), much more time than was actually
available on the early earth, and theoretically maximal reaction rates among constituent
© by Stephen C. Meyer. All Rights Reserved.
15
monomers (i.e., the constituent parts of proteins, DNA and RNA). Such calculations have
invariably shown that the probability of obtaining functionally sequenced
biomacromolecules at random is, in Prigogine’s words, “vanishingly small . . .even on the
scale of . . .billions of years” [56]. As Cairns-Smith wrote in 1971:
Blind chance…is very limited. Low-levels of cooperation he [blind chance] can
produce exceedingly easily (the equivalent of letters and small words), but he
becomes very quickly incompetent as the amount of organization increases. Very
soon indeed long waiting periods and massive material resources become
irrelevant. [55, p. 95]
 
I checked with myself again just to be sure and was assured that I was correct so I doubt my posts were the cause 😉
Yeah - I once though I was wrong but I was mistaken…😃 😉

So we are both right. :hmmm: I’ll flip you for it. 🙂
 
Challenging Fossil of a Little Fish

CHENGJIANG, China — The fish-like creature was hardly more than an inch long, but its discovery in the rocks of southern China was a big deal. The 530-million-year-old fossil, dubbed Haikouella, had the barest beginning of a spinal cord, making it the oldest animal ever found whose body shape resembled modern vertebrates.

In the Nature article announcing his latest findings, Jun-Yuan Chen and his colleagues reported dryly that the ancient fish “will add to the debate on the evolutionary transition from invertebrate to vertebrate.”

“Neo-Darwinism is dead,” said Eric Davidson, a geneticist and textbook writer at the California Institute of Technology. He joined a recent gathering of 60 scientists from around the world near Chengjiang, where Chen had found his first fishlike impressions of Haikouella five years ago.

Today, paleontologists still lack viable ancestors for the Cambrian’s forty or more animal phyla. Most researchers explain this by assuming that Precambrian animals were simply too small or too soft to leave a fossil record, or that conditions were unfavorable to fossilization.

In fact, the pair had failed to find any recognizable body plans showing steps along the way toward the complex Cambrian animals with their legs, antennae, eyes and other features.

What they had actually proved was that Chinese phosphate is fully capable of preserving whatever animals may have lived there in Precambrian times. Because they found sponges and sponge embryos in abundance, researchers are no longer so confident that Precambrian animals were too soft or too small to be preserved.

“I think this is a major mystery in paleontology,” said Chen. “Before the Cambrian, we should see a number of steps: differentiation of cells, differentiation of tissue, of dorsal and ventral, right and left. But we don’t have strong evidence for any of these.”

Taiwanese biologist Li was also direct: “No evolution theory can explain these kinds of phenomena.”
 
The current idea behind species is two groups become isolated and can no longer interbreed.
Correct.
However, my only issue is the idea that some novel organ could gradually appear in a macro creature.
There is no need for a new organ to appear for a new species. Both horses and donkeys share the same set of organs yet they cannot produce fertile hybrids.
A wing on its way to becoming a wing won’t allow the macro creature to fly.
But it might help it glide a bit further, attract mates with its display or help with heat exchange. A half-wing can have uses other than flying.
A light sensitive spot has quite a ways to go before it becomes an eyeball, and stereo vision requires some precise distance between the two eyeballs to allow for full function.
A light sensitive spot is still useful. Are your eyes useless because a hawk’s eyes are sharper? Your vision would be a useless fuzzy blur to a hawk trying to see a mouse in undergrowth from hundreds of feet in the air. There are many different types of eye, some sharper, some not so sharp. All are useful to the organism that carries them.
The function of a gill is far enough removed from the function of a lung to make any connection between the two imaginative and highly doubtful.
Correct, lungs did not evolve from gills. Gills evolved from the neck region while lungs evolved later from the gut. Many amphibians have both.
Even the experts cannot produce a bona fide transitional fossil
This is creationist rubbish. We have many transitional fossils in many series. The problem is that creationists redefine “transitional” in their own way. There are indeed no creationist-transitionals. There are many evolution-transitionals.

Try the water to land transition:* fish with fins.
  • fish with fins on stumps.
  • fish with fins on stumps with knees.
  • fish with fins on stumps with knees and ankles.
  • fish with fins on stumps/legs with knees, ankles and toes.
  • amphibians with fins on stumps/legs with knees, ankles and toes.
  • amphibians with legs with knees, ankles and toes.
How is that not transitional?

rossum
 
I am afraid that this is not correct for several reasons:
  1. I don’t know of a single geneticist or molecular biologist working in palaeo-demography (including Cavalli-Sforza) who has claimed or is claiming that the molecular evidence is consistent with a bottleneck of two in the human lineage. On the contrary, the evidence precludes that hypothesis.
  2. I think you have badly misunderstood what you have read. I can’t find any statement in the History and Geography of Human Genes by Cavalli-Sforza et al which ‘supports the fact of a first pair of human parents’. In fact the authors go out of their way to debunk that idea. With regard to mitochondrial DNA coalescence and the mtDNA phylogenetic tree they say:
“There have been many misunderstandings amongst readers of these results on their exact meaning…the reconstruction of a single woman who may have lived 200 kya and carried an mtDNA type ancestral to all the types of mtDNA found in living human populations has been misunderstood not only by laymen but by a few distinguished colleagues, who have accepted it as evidence that 200 kya there lived a single woman from whom all living humans descend. The widepread use, especially in popular magazines, of the word ‘Eve’ for naming the first mitochondrial ancestor of all mitochondria found in modern populations was probably responsible for generating this common misunderstanding…There is absolutely no evidence from mtDNA work that the human population went through a bottleneck in which there was only one (or few) women.” (Page 86)

Note that 15 years have passed since that was written, and ‘distinguished colleagues’ no longer make the mistake that Cavalli-Sforza tasked them with, although laymen aplenty still do.
  1. And the fact that this book is 15 years old and pre-dates the sequencing of the human genome means that even if it supported what you say, which it doesn’t, it is hardly the last word on the subject. A huge quantity of work has been published since then, and *none *of it supports the notion of a bottleneck of two individuals while some it precludes such an idea.
Alec
evolutionpages.com/Mteve_not_biblical_eve.htm
:confused: I can’t reply fully to your objection at this time because I was relying on memory and perhaps I have wrongly recalled text and author. So, I will have to do a little homework. But the view I had in mind does not involve a misunderstanding of Mitochondrial Eve. That is, it is not based on the common misunderstanding of that particular theory. Obviously, some folks have been easily mislead by the word “Eve”.

Setting aside your objection related to ME, the main point of evolution is common ancestry. And I was thinking of the issue more so according to monogenism and polygenism, which would both be true at different times and points on the evolutionary tree.

So, perhaps you can give your perspective on the subject stated in the following manner. And I may risk saying this scenario is consistent with what Cavalli-Sforza has said.

If one traces their ancestry beginning with their parents, they will encounter an increasing number of sets of direct ancestors: 4, then 8 grandparents, and so on. The numbers increase exponentially. Yet if one goes back far enough in time, those numbers begin to decrease due to the decreasing size of the earth’s population. Eventually, one would arrive at a first pair of ancestors. Otherwise, their would be no common descent, no evolution.
 
If one traces their ancestry beginning with their parents, they will encounter an increasing number of sets of direct ancestors: 4, then 8 grandparents, and so on. The numbers increase exponentially. Yet if one goes back far enough in time, those numbers begin to decrease due to the decreasing size of the earth’s population.
Correct so far.
Eventually, one would arrive at a first pair of ancestors. Otherwise, their would be no common descent, no evolution.
Here you are in error. Evolution is a population phenomenon, and we would arrive at a small population of ancestors, not a single pair. The smallest scientific estimate I have seen for the minimum human population is 1,000 breeding pairs, though most estimates are much closer to a minimum of 10,000 breeding pairs.

Each of us carries two copies of (almost) every gene. Some genes are different in the population - some have a version (allele) for blue eyes while other have a version for brown eyes. If there are 100 variants of a gene then there must have been at least 50 breeding individuals (at two copies per individual) alive to carry all those copies and pass them on.

Given known mutation rates, the known number of different versions of each gene, and the known number of those versions we share with chimpanzees we can make estimates of the minimum human population size. As I said, the minimum estimate I have seen is 1,000 breeding pairs - 2,000 individuals of breeding age plus however many too young or too old to breed. The human population was never as low as two.

It is possible that our ancestors’ population was smaller earlier, but that would have been before we diverged from the chimpanzees and so the animals involved would not yet have been human.

rossum
 
Correct so far.
Here you are in error. Evolution is a population phenomenon, and we would arrive at a small population of ancestors, not a single pair. The smallest scientific estimate I have seen for the minimum human population is 1,000 breeding pairs, though most estimates are much closer to a minimum of 10,000 breeding pairs.
I am familiar with this hypothesis. Perhaps you can unpack it, showing your interpretation. That is, give a possible ancestral history of the 1,000 - 10,000 or so pairs, i.e. the origins of this population.
 
I’d like to add my expertise at this argument if you will. Here’ where we’re at:
  1. I don’t know a single geneticist.
  2. I think you have badly misunderstood what you have read.
  3. There have been many misunderstandings.
  4. 15 years have past.
  5. A huge quantity of work has been published
Therefore, … I don’t know.🤷
Originally Posted by hecd2 forums.catholic-questions.org/images/buttons_khaki/viewpost.gif
I am afraid that this is not correct for several reasons:
  1. I don’t know of a single geneticist or molecular biologist working in palaeo-demography (including Cavalli-Sforza) who has claimed or is claiming that the molecular evidence is consistent with a bottleneck of two in the human lineage. On the contrary, the evidence precludes that hypothesis.
  1. I think you have badly misunderstood what you have read. I can’t find any statement in the History and Geography of Human Genes by Cavalli-Sforza et al which ‘supports the fact of a first pair of human parents’. In fact the authors go out of their way to debunk that idea. With regard to mitochondrial DNA coalescence and the mtDNA phylogenetic tree they say:
“There have been many misunderstandings amongst readers of these results on their exact meaning…the reconstruction of a single woman who may have lived 200 kya and carried an mtDNA type ancestral to all the types of mtDNA found in living human populations has been misunderstood not only by laymen but by a few distinguished colleagues, who have accepted it as evidence that 200 kya there lived a single woman from whom all living humans descend. The widepread use, especially in popular magazines, of the word ‘Eve’ for naming the first mitochondrial ancestor of all mitochondria found in modern populations was probably responsible for generating this common misunderstanding…There is absolutely no evidence from mtDNA work that the human population went through a bottleneck in which there was only one (or few) women.” (Page 86)
Note that 15 years have passed since that was written, and ‘distinguished colleagues’ no longer make the mistake that Cavalli-Sforza tasked them with, although laymen aplenty still do.
  1. And the fact that this book is 15 years old and pre-dates the sequencing of the human genome means that even if it supported what you say, which it doesn’t, it is hardly the last word on the subject. A huge quantity of work has been published since then, and *none *of it supports the notion of a bottleneck of two individuals while some it precludes such an idea.
 
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