The Arians were not slow to avenge themselves. On vague pretexts the emperor banished Meletius to his native Armenia. He had occupied his see less than a month.
This exile was **the immediate cause of a long and deplorable schism between the Catholics of Antioch, henceforth divided into Meletians and Eustathians. **
Though the election of Meletius was beyond contestation, the hot-headed Lucifer Cagliari yielded to the solicitations of the opposing faction, and instead of temporizing and awaiting Meletius’s approaching return from exile, assisted by two confessors **he hastily consecrated as Bishop of Antioch the Eustathian leader, Paulinus. This unwise measure was a great calamity, for it definitively established the schism. **Meletius and his adherents were not responsible, and it is a peculiar injustice of history that this division should be known as the Meletian schism when the Eustathians or Paulinians were alone answerable for it. Meletius’s return soon followed, also the arrival of Eusebius of Vercelli, but he could accomplish nothing under the circumstances.
Just then St. Athanasius came to Antioch by order of the emperor, and expressed to Meletius his wish of entering into communion with him. Meletius, ill-advised, delayed answering him, and St. Athanasius went away leaving with Paulinus, whom he had not yet recognized as bishop, the declaration that he admitted him to his communion. Such blundering resulted in sad consequences for the Meletian cause. The moderation constantly shown by Athanasius, who thoroughly believed in Meletius’s orthodoxy, was not found in his successor, Peter of Alexandria, who did not conceal his belief that Meletius was an heretic.
This new exile, owing to a lull in the persecution, was of short duration, and probably in 367 **Meletius took up again the government of his see. It was then that John, the future Chrysostom, entered the ranks of the clergy. **
At this time St. Basil occupied the see of Cæsarea (370) and was a strong supporter of Meletius. With rare insight Basil thoroughly understood the situation, which made impossible the restoration of religious peace in the East. It was clear that the antagonism between Athanasius and Meletius protracted endlessly the conflict. Meletius, the only legitimate Bishop of Antioch, was the only acceptable one for the East; unfortunately he was going into exile for the third time. In these circumstances Basil began negotiations with Meletius and Athanasius for the pacification of the East.
This important conversion won over to the intruders St. Jerome and Pope Damasus; the very next year, and without any declaration concerning the schism, **the pope showed a decided preference for Paulinus, recognized him as bishop, greeted him as brother, and considered him papal legate in the East.**Great was the consternation of Meletius and his community, which in the absence of the natural leader was still governed by Flavius and Diodorus, encouraged by the presence of the monk Aphrates and the support of St. Basil.
St. Jerome entered into the conflict, perhaps without having a thorough knowledge of the situation. Rejecting Meletius, Vitalian, and Paulinus, he made a direct appeal to Pope Damasus in a letter still famous, but which the pope did not answer.
Discontented, Jerome returned to Antioch, let himself be ordained presbyter by Paulinus, and became the echo of Paulinist imputations against Meletius and his following.
**In 379 Meletius held a council of 150 bishops in order to assure the triumph of orthodoxy in the East, and published a profession of faith which was to meet the approval of the Council of Constantinople (382). The end of the schism was near at hand.**either bishop made it possible for the survivor to exercise full authority without hurting pride or discipline. This solution Meletius recognized as early as 381, but his friendly and peace- making proposals were rejected by Paulinus who refused to come to any agreement or settlement.
In the absence of the Bishop of Alexandria, the presidency rightfully fell to the Bishop of Antioch, whom the Emperor Theodosius received with marked deference, nor was the imperial favour unprofitable to Meletius in his quality of president of the assembly. It began by **electing Gregory of Nazianzus Bishop of Constantinople, and to the great satisfaction of the orthodox it was Meletius who enthroned him.****The Council immediately proceeded to confirm the Nicene faith, but during this important session Meletius died almost suddenly. **Feeling his end was near, he spent his remaining days re-emphasizing his eagerness for unity and peace.