Participation in Covid-19 vaccine Phase 3 clinical trial - ultimate act of charity?

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arvo

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John 15:13
“No one has greater love than this, to lay down one’s life for one’s friends.”
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16th March of 2020 was the first date when the first injection of the new Covid-19 vaccine was made to the man. It took 2 months (January-March) to prepare the vaccine from deciphering the genome of SARS-CoV2 virus to the preparation of the vaccine and first non-human tests. Just 2 months, because the firm used the established framework for generating the vaccine from the virus genome. Now - almost 6 months are gone, the vaccine is the same, only the dosage is being tuned and the completion of phase 3 clinical tests are all that is required before the vaccine to go the masses.

The recruitment of volunteers for the phase 3 clinical trial is the only obstacle for the successful completion of the clinical tests. As I understand, then the firms and the medical agencies have established the certain requirements on the participating number which should be achieved before announcing that enough data and enough certainty has been achieved before to make the final evaluation of the vaccine and declaration it to be safe.

Both biggest programs (US and UK) for phase 3 vaccine trials are still open for recruitment, there are almost 20.000 volunteers but more volunteers are required.

So - what is your discernment? Is this the single moment of your life in which you can risk your life for your neighbour? Besides - the profit/price ratio (if we can say so) is very high - completed vaccine vs quite safe, monitored and unpainfull vaccine shot.

What prohibits you from the enrolling in vaccine trials?

As for me personally - I offered myself for clinical trials already in the end of March in my country. They rejected me, because there was no active clinical trial in my country. And there is still no single clinical trial in my country. But I would certainly take the shot (or more) if there was ongoing Covid-19 vaccine clinical trial in my country. Actually - it is with lot of self-interest - I am passing lot of activities, concerts, exhibition that I would have gone if I had had the vaccine.
 
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I very admire people who volunteer for clinical trials and wish them the best of luck and also gratitude 🙂

Right now, I have too many responsibilities to family that it wouldn’t make sense for me to take any unnecessary risks.
 
I just wanted to note how happy you, the Americans, English people and people from other countries with ongoing trials are - you have the opportunity to make the distinction and to end this nightmare and to contribute to the science, well-being, life and economics of your neighbors. There are countries in which the firms are not wiling to make trials, e.g., the population is too small or the infection rate is small (vaccine trials for effectiveness usually require high infection rate).

I really hope that you appreciate the opportunities you have to do this charity!

Just wanted to add another note: clinical trials are made on human beings and they follow the preclinical trials that are made on non-human model organisms. Clinical trials have 3 phase: 1) phase 1 - safety, that the side-effects are non-existan or small; 2) phase 2 - effectiveness in small focus groups; 3) phase 3 - effectiveness in population wide studies.

The largest vaccines are on Phase 3 trials, that means that their safety has already been prove with scientific rigour. Of course, additional safety issues can be discovered in phases 2 and 3, but the biggest threats are already been handled in phase 1 trials. A lot of drugs stop at the phase 1 trials - is they are not safe.
 
arvo said:
Actually - it is with lot of self-interest - I am passing lot of activities, concerts, exhibition that I would have gone if I had had the vaccine.
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If you get into a trial, you won’t know if you received the vaccine or a placebo. Only half of the volunteers get the vaccine. The trials are “double blind”, the researchers don’t know either. They match up the numbers at the end of the trial…and the trial goes on for two years.

The trials will continue, even after a vaccine is found that is both effective and safe, because they need to determine if it needs to be given just once, or annually, or on some other cadence.
 
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You are right, I forgot about placebo.

Well, yes, that results in the increase in the “price” and the level of suffering of this charity work. Not nice. From the other hand, it is also the increase of deposit or our good deeds that we are putting at the feet of our Lord and in the common deposit of our Church for the benefit of others.
 
arvo said:
16th March of 2020 was the first date when the first injection of the new Covid-19 vaccine was made to the man. It took 2 months (January-March) to prepare the vaccine from deciphering the genome of SARS-CoV2 virus to the preparation of the vaccine and first non-human tests. Just 2 months, because the firm used the established framework for generating the vaccine from the virus genome.
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I’m assuming that you mean that aborted babies were used in the making of this vaccine.
 
I also think one bonus is that they monitor your overall health during the trial. For example, there was a volunteer in the Oxford trial who showed health issues and the experts found that it was not related to the vaccine but to undiagnosed multiple scleroris in early stages.
 
Elf01 said:
I’m assuming that you mean that aborted babies were used in the making of this vaccine.
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I checked and it may be indeed true - the vaccine which I referred and which is the most developed in clinical trials in the US, can be linked with the cell line of aborted fetus. But this issue (mostly about vaccination, but I guess, that it can be applied to the clinical trials as well) is addressed by the note Note on Italian vaccine issue which is published cooperatively by:
  • The Pontifical Academy of Life (it is one of the almost dozen pontifical academies in the Roman Curia http://www.vatican.va/roman_curia/index.htm, some of the pontifical academies (e.g. Pontifical Academy of Sciences) has very venerable history);
  • the National Office of Health Pastoral Care of the Italian Conference of Catholic Bishops (I don’t now how the bishop of Rome is connected to this Conference);
  • the Association of Italian Catholic Doctors
You can read yourself this note, all the important parts are in bold, especially:
The technical characteristics of the production of the vaccines most commonly used in childhood lead us to exclude that there is a morally relevant cooperation between those who use these vaccines today and the practice of voluntary abortion. Hence, we believe that all clinically recommended vaccinations can be used with a clear conscience and that the use of such vaccines does not signify some sort of cooperation with voluntary abortion.
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But, as always - the consciences is the highest ruler of owns behavior. Someone may still consider it immorally to use such vaccines (and instead, he/she can invest in and support moral vaccines) - it can be in accordance to the state of his/her conscience. Similarly - my state of conscience has a bit unorthodox position regarding intimacy and adelphopoiesis liturgy for SSA couples, but it’s all fine. We all are on the path towards our Lord and the way may not be straight and wide, indeed, the opposite was told by our Lord.

I understand that there is not necessity to use fetus cell lines today, I guess - cell lines (interminably dividing cell cultures) can be derived from born people and it may even be induced by partial or full reprogramming.
 
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I could not justify the risk.

There has been far too much corruption in the vaccine safety studies over the years. For example

Methodological Issues and Evidence of Malfeasance in Research Purporting to Show Thimerosal in Vaccines Is Safe
Brian Hooker,1 Janet Kern,2,3 David Geier,2 Boyd Haley,4 Lisa Sykes,5 Paul King,5 and Mark Geier2


The claims of whistleblowers from the CDC and NIH have not been adequately investigated and publicly debated. It seems there has been an effort to downplay these incidents in the corportate media funded by Big Pharma. For example
(Please Note: This uploaded content is no longer available.)



Finally the treatments for Covid are far too good. There is little need for a vaccine and no need for the vast majority of people under age 50.

A professor who was a consultant for the French and WHO vaccine programs explains his view similar to mine in this 5 minute clip.

 
Before I had children, I participated in several clinical trials for various cancers at a major cancer centre. They gave me medical care (and I had internationally renowned surgeons who took very good care of me–I wouldn’t be here without them). It still cost travel and for a ‘guardian’ companion. I’m glad I participated but it was no small burden. I think it completely depends on the trial. An accelerated vaccine? Even if was healthy, I’m not sure I’d risk it, having kids to raise.
 
Has it been published whether the person has received placebo or the vaccine ? Not familiar with what the usual protocol of disclosure is for these cases during the course of this type of trial process.
 
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I guess that at some point the person will be informed whether he/she has received the vaccine of placebo. That must definitely happen, because int he case of placebo she will have to receive the real vaccine when that will be confirmed and at that point she will be informed about this status.

I have read about experiences of others and mostly - people can quite certainly say that they are receiving vaccine not placebo - there are some signs of reaction and it is normal for vaccines.

This week I received flu vaccine for this season (against all 4 types of flu) and I had also some minor reaction. It was not fun, especially for me who has some hypohondria, but it was not anything serious as well.

ModernaTX currently has given second (last dose) to 15.000 people from 25.000 totally (i.e. some are dropped and some are still in pipeline), but Clinical Research protocol for the COVE study required that 30.000 people should receive the trial vaccine. So - more people are required.

Some says that 1500-2000 $ are paid to the volunteers to compensated for the travelling and time consumption expenditure. Some articles are saying that the generosity and the enthusiasm of the people are incredible and quite differs from the other clinical trials.

This is really the momentum of charity, of expression of the Catholic, Christian soul! What a gift!
 
I don’t volunteer my body to be anyone’s guineapig and I will refuse any vaccines for as long as I’m able.
 
I probably wouldn’t volunteer unless I really studied how the research is going.

There’s such a rush that I’d worry about hasty decisions and a “warp speed” mentality that might lead to mistakes, oversights and that might push patient safety to the margins.
 
Formon said:
I don’t volunteer my body to be anyone’s guineapig and I will refuse any vaccines for as long as I’m able.
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Same here. I don’t oppose vaccines in general, but not new ones. Same with medications. Just because there are no visible side effects in the short term doesn’t guarantee that the medication is safe.
 
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