It seems to me that gender must come down to DNA, how else would it be defined? The question is can DNA ever be altered to match a physical surgical change?
Yes most easily through bone marrow transplant though in some cases it is not needed as the apparently male at birth transsexual already has 46XX or 47XXY chromosomes.
Bone marrow transplant replaces the entire bloodstream’s DNA within weeks but it takes approximately seven years for the majority of the body’s cells to be replaced by stem cells generated by the donor tissue. As the stem cells are in the correct environment the sexual and other anatomy does not change just the DNA.
Bone marrow-derived cells from male donors can compose endometrial glands in female transplant recipients by Ikoma et al in
Am J Obstet Gynecol. 2009 Dec;201(6):608.e1-8 :
Code:
**RESULTS**: All recipients had donor-derived Y chromosome-positive endometrial cells, accounting for 0.6-8.4% of glandular epithelial cells and 8.2-9.8% of stromal cells. Most of the endometrial glands were chimeric, consisting of both donor-derived and recipient cells.
**CONCLUSION:** Donor-derived cells are capable of composing endometrium in recipients, even those of the opposite sex.
In simple terms the patient’s ovaries are slowly becoming genetically the same as the cells of the male donor. At the time of testing most of the glands were chimeric meaning a mixture of both donor-DNA and recipient-DNA cells.
Transplanted human bone marrow cells generate new brain cells by Crain BJ, Tran SD, Mezey E. in
J Neurol Sci. 2005 Jun 15;233(1-2):121-3 :
The female patients in this study had received either bone marrow or stem cell (CD34+ enriched) transplants from their brothers. Double labeling for X- and Y-chromosomes showed that Y-labeled buccal cells could not be explained by fusion. Genotyping studies of one patient, her brother, and her son ruled out the possibility of microchimerism. Whether, and under what circumstances, some form of bone marrow transplantation might provide adequate number of cells capable of replacing lost brain cells or enhancing their function will require additional studies.
In other words the cells were entirely of the DNA of the male donor(s) and not some microhybrid or fusions with the recipients DNA they were genetically identical to the donor’s cells.
Similar effects are observable in 45X/46XX/46XY/47XXY mosaics as the 45X and 47XXY cells get selected against during cellular turnover and so a patient who is naturally mostly 45X with some 46XY will become more 46XY over time and a patient who is mostly 47XXY with some 46XX will become more 46XX over time. A 45X genotype results in a prepubescent female somatic form usually while a 47XXY genotype results in an anomalous male somatic form usually but there are always exceptions due to hormonal environment in the womb.
It is for this reason that we must rely solely upon what Holy Mother Church tells us is the case and not be misled by genital appearance at birth genital appearance later anatomy of the brain or indeed any biological reality. If the Church says that someone is male based on their chromosomes even though they have given birth to three children then they are male. If the Church says that someone is female based on the shape of their genitalia at birth even though they have fathered children then they are female. In both cases the sexual congress resulting in the production of children is inherently disordered and sinful as it is homosexual.
That this is the correct course of action ignoring mere observations of reality is proven by the Holy Father’s speech (while still cardinal) at La Spexia University on May 15 1990
The Church at the time of Galileo kept much more closely to reason than did Galileo himself, and she took into consideration the ethical and social consequences of Galileo’s teaching too. Her verdict against Galileo was rational and just, and the revision of this verdict can be justified only on the grounds of what is politically opportune
Science is only concerned with Facts while the Church is concerned with Truth and Theology is the Queen of Sciences. We must never let scientific logic and data over-rule divinely inspired Reason which takes into account the social and ethical consequences of our conclusions.