Thanks for this Topic, it is a good one.
Suffering is hard to understand, the WHY of it. Why do people get born into suffering, including genetic errors, and so forth.
I believe that God knew those in one way or another prior to their birth into suffering into this world, and these spirits took apon themselves a spirit body, and then born into a crippled human body. This is a very complex issue that can only be solved by our Love of other who are suffering, and of helping these people.
When able bodied people help those in need, having a great deal of love, this helps both the needs of the handicapped and helps the caregivers to grow in Spirit and Love. The large Natural Disasters do help to get many people to put down their pens and calculators, and come out to help with resue and cleanup, so these things can help many people to grow in Spirit and Love.
This is a Topic I learned a great deal in the study of Near Death Experiences for many years, since the 1980’s, that all the suffering is for a reason, sometimes beyond our understanding, but the Suffering including Natural Disasters are potentially for growth in Spirit and Love, and Compassion of others, so it does have a purpose.
Now when we obtained a Spirit Body and a Physical Body, we are now effected by Other’s Sin, and of our own Sin, while in a human body, and as a result our illnesses can end our lives early, but any unforgiven sin, like ones that cannot be forgiven, these Sins can cause a Second Death, which is both a casting out from God’s presence, and the Loss of the Spirit Body(2nd Death), in the Lake of Fire, at the time of the Final Judgement.( This is my best guess as to what I’ve learned)