You want to go over autonomy? First from the Catechism we see one application of mistaken autonomy, one opposed to the teaching of the Church.
2126 Atheism is often based on a false conception of human autonomy, exaggerated to the point of refusing any dependence on God.63 Yet, "to acknowledge God is in no way to oppose the dignity of man, since such dignity is grounded and brought to perfection in God. . . . "64 "For the Church knows full well that her message is in harmony with the most secret desires of the human heart."65
Secondly, read some excerpts from the CDF
Doctrinal Note on The Participation of Catholics in Political Life, which are addressing the confusion of autonomy between political and civil vs. religious.
vatican.va/roman_curia/congregations/cfaith/documents/rc_con_cfaith_doc_20021124_politica_en.html:
For Catholic moral doctrine, the rightful autonomy of the political or civil sphere from that of religion and the Church – but not from that of morality – is a value that has been attained and recognized by the Catholic Church and belongs to inheritance of contemporary civilization.[23] John Paul II has warned many times of the dangers which follow from confusion between the religious and political spheres.
…
By its interventions in this area, the Church’s Magisterium does not wish to exercise political power or eliminate the freedom of opinion of Catholics regarding contingent questions. Instead, it intends – as is its proper function – to instruct and illuminate the consciences of the faithful, particularly those involved in political life, so that their actions may always serve the integral promotion of the human person and the common good.