R
ribozyme
Guest
In this thread, I will not promote a political agenda such as “socialism” or “egalitarianism” or European price caps, nor will I shake my fist at “big pharma.” I have to congratulate myself for not repining against the profits of drug companies in another thread with the exception of AstraZeneca’s profits for a specific enantiomer (esomaprazole) of a proton pump inhibitor. But one can obviously see through my socialist agenda in that thread given that I have used the * international non-proprietary names * for substances instead of their commercial names (eg. erlotinib, imatinib, bevacizumab; respectively Tarceva, Gleevac, Avastin) as I do not respect private property. (Of course, I was joking during my last sentence and I do think patents are necessary for innovation, but I’ll retain my habit of using the non-proprietary names.)
However, the focus of this thread is to bring awareness to a polemical irony about capitalism and Catholic belief. I remember a similar thread that advocates boycotts to Planned Parenthood. Should the capitalistic drug companies be endowed with the right to profit of their labor? If capitalistic drug companies want to maximize their profits, should they have the right to do so? However, what if that right involves using human embryonic stem cells and requires the destruction of an embryo?
AstraZeneca, Roche, and GlaxoSmithKline should be added to the list of companies that have committed “mortal sin” by endorsing embryonic stem cell research.
Certain stem cell advances may allow scientists to accomplish this with using embryonic stem cells, but my main point is that these drug companies were willing to trespass on the sanctity of human life (defined in the Catholic sense) in order to maximize profits.
As a utilitarian, I have no reason to have any moral qualms about this. Unfortunately, after preclinical development, it is akin to a Hail Mary pass for a drug to make it to the market as a compound need to go through a gauntlet of Phase I, II, and III clinical trials to make it to the clinic. As a result of extensive clinical testing, only 10% of these compounds make it out of the pipeline. I suppose using embryos to improve the success rates would be desirable and cost effective as it would prune out some “failure” molecules. Also, this can help the companies reap the benefits of capitalism by creating more blockbusters and further enriching themselves. Greed is good, right?
Since embryos do not have interests nor can they suffer, I regard the failure of bringing a therapeutic drug to market a larger catastrophe than using embryos for clinical or research purposes.
http://upload.wikimedia.org/wikipedia/commons/thumb/a/a0/Torcetrapib.png/200px-Torcetrapib.png
Now that is something synonymous with failure; an $800 million dollar failure, catastrophe, debacle, fiasco!
Shouldn’t the thought of taking torcetrapib strike terror in dyslipidemic Catholics? The torcetrapib + atorvastatin arm of a 15k patient Phase III trial experienced a higher mortality rate than the placebo + atorvastatin arm [content.nejm.org/cgi/content/abstract/357/21/2109]](http://content.nejm.org/cgi/content/abstract/357/21/2109]). In my opinion, this is one reason (and rofecoxib [the “V” word synonymous with “lawsuit” cough vioxx cough]) why expensive clinical trials should be conducted and this probably justifies some high drug prices. If using stem cells can deter such a tragedy and wasteful use of $800 million dollars, I suppose the use of embryonic stem cells can be justified.
However, the focus of this thread is to bring awareness to a polemical irony about capitalism and Catholic belief. I remember a similar thread that advocates boycotts to Planned Parenthood. Should the capitalistic drug companies be endowed with the right to profit of their labor? If capitalistic drug companies want to maximize their profits, should they have the right to do so? However, what if that right involves using human embryonic stem cells and requires the destruction of an embryo?
“GlaxoSmithKline, AstraZeneca and Roche have each paid 100,000 pounds ($200,000) to help fund the first year’s work, while the British government is contributing 750,000 pounds.
…
Stem cells are the body’s master cell, acting as a source for the body’s cells and tissues. Embryonic stem cells are the most malleable, but their use in research is opposed by some people because it involves destruction of a human embryo.
Britain, however, has encouraged such research and science minister Ian Pearson said the new collaboration was an example of the government’s commitment to the field.
reuters.com/article/healthNews/idUSL0233214720071002?feedType=RSS&feedName=healthNews&pageNumber=1&virtualBrandChannel=0By working across academic and industrial laboratories, the project aims to develop effective ways of using human embryonic stem cells to screen for potentially dangerous side effects of new drugs before they go into clinical trials.”
AstraZeneca, Roche, and GlaxoSmithKline should be added to the list of companies that have committed “mortal sin” by endorsing embryonic stem cell research.
Certain stem cell advances may allow scientists to accomplish this with using embryonic stem cells, but my main point is that these drug companies were willing to trespass on the sanctity of human life (defined in the Catholic sense) in order to maximize profits.
As a utilitarian, I have no reason to have any moral qualms about this. Unfortunately, after preclinical development, it is akin to a Hail Mary pass for a drug to make it to the market as a compound need to go through a gauntlet of Phase I, II, and III clinical trials to make it to the clinic. As a result of extensive clinical testing, only 10% of these compounds make it out of the pipeline. I suppose using embryos to improve the success rates would be desirable and cost effective as it would prune out some “failure” molecules. Also, this can help the companies reap the benefits of capitalism by creating more blockbusters and further enriching themselves. Greed is good, right?
Since embryos do not have interests nor can they suffer, I regard the failure of bringing a therapeutic drug to market a larger catastrophe than using embryos for clinical or research purposes.
http://upload.wikimedia.org/wikipedia/commons/thumb/a/a0/Torcetrapib.png/200px-Torcetrapib.png
Now that is something synonymous with failure; an $800 million dollar failure, catastrophe, debacle, fiasco!
Shouldn’t the thought of taking torcetrapib strike terror in dyslipidemic Catholics? The torcetrapib + atorvastatin arm of a 15k patient Phase III trial experienced a higher mortality rate than the placebo + atorvastatin arm [content.nejm.org/cgi/content/abstract/357/21/2109]](http://content.nejm.org/cgi/content/abstract/357/21/2109]). In my opinion, this is one reason (and rofecoxib [the “V” word synonymous with “lawsuit” cough vioxx cough]) why expensive clinical trials should be conducted and this probably justifies some high drug prices. If using stem cells can deter such a tragedy and wasteful use of $800 million dollars, I suppose the use of embryonic stem cells can be justified.