$10,000 x 4 years is not a crazy, horrific number compared to a pharmacists salary. Over a standard 10 year repayment plan, it is ~200 more per month compared to the other school, while you could easily expect to earn $5000 a month after taxes and benefits. Within two years of graduation, nobody cares what school you went to.
Everyday, I am seeing a new pharmacy, whether stand-alone or in a grocery store, being built somewhere, and each one will need at least two full time pharmacists, so the field is still growing. Two opened within 5 miles of me in the past few years, and I live in a small town.
The finances and relative prestige should not necessarily be your driving factor. Consider the cost of not finishing your studies. If you only complete say two years of study, you will still have tens of thousand of debt to pay off. If the individual attention at the smaller school provides a significantly increased chance of completing your studies, the extra tuition, from a risk assessment perspective, may be worth it to you.