You are dropping back into metaphysics again.
We are discussing reality, which is not a subjective phenomenon. Metaphysics, which addresses those aspects that have to do with the structure of being, can only point to what exists, but are themselves otherwise intellectualizations that approach the truth, but can be in error. They are spoken of as a realized or revealed knowledge, which cannot be logically derived, since the concepts that do not include them are insufficient.
This is not metaphysics but science.
As to random change in the genome being destructive, one need only understand that the series of base pairs in DNA is utilized by cellular processes and structures to produce a series of amino acids, that constitute specific proteins, and that any random chemical change will result in change in the protein structure. Each different series of amino acids is arranged, by virtue of their electrostatic interactions, into a particular shape, which gives the protein its function, be it structural, enzymatic or as the switch which begins a cascade of events within and outside the cell.
The effect of random chemical change in the genome is best understood when we think cancer. The cause may be a toxin such as tobacco smoke or benzene, radiation, as in too much sun or lack of protection when undergoing particular scans, viruses, such as papilloma and hepatitis C, or simply the noise that exists in any system and results in a glitch during the process of reproduction, running more of a risk when cells are having to reproduce more frequently as a result of chronic ongoing damage, as in stomach or esophageal cancer. The activity of molecules and atoms, outside the regulatory influence of the over-riding order found in the cell, is chaotic to that which is necessary for life.
If you don’t want to die, then do not get born.
Exactly, one is born, created from nothing, utilizing matter that is moulded into the bodily dimension that is the person. We do develop however, and at a certain point, growth is replaced on a physical level by a de-composition of those material structures, and once we are dead, it completely returns to the dust that we are. Similarly, on a larger scale what we observe is devolution. The appearance of evolution is the result of successive creative events, which saw the coming into being of increasingly complex forms.
