From the catechism:
675 Before Christ’s second coming the Church must pass through a final trial that will shake the faith of many believers.574 The persecution that accompanies her pilgrimage on earth575 will unveil the “mystery of iniquity” in the form of a religious deception offering men an apparent solution to their problems at the price of apostasy from the truth. The supreme religious deception is that of the Antichrist, a pseudo-messianism by which man glorifies himself in place of God and of his Messiah come in the flesh.576
676 The Antichrist’s deception already begins to take shape in the world every time the claim is made to realize within history that messianic hope which can only be realized beyond history through the eschatological judgment. The Church has rejected even modified forms of this falsification of the kingdom to come under the name of millenarianism,577 especially the “intrinsically perverse” political form of a secular messianism.
Not much here about gender. Let’s check scriptural references to the antichrist:
1 John 2:18
Little children, it is the last hour; and as you have heard that Antichrist cometh, even now there are become many Antichrists: whereby we know that it is the last hour.
1 John 2:22
Who is a liar, but
he who denieth that Jesus is the Christ? This is Antichrist, who denieth the Father, and the Son.
1 John 4:3
And every spirit that dissolveth Jesus, is not of God: and this is Antichrist, of whom you have heard that
he cometh, and he is now already in the world.
2 John 1:7
For many seducers are gone out into the world, who confess not that Jesus Christ is come in the flesh: this is a seducer and an antichrist.
Here, the masculine pronoun is probably a reflection of the culture in which John wrote.
As a man who has been married for 32 years, I dare not risk an opinion on this subject
