While some verses might be easier to understand than others.
Overall:
NO, Scripture does not interpret Scripture, or better yet: we are not able to interpret Scriptures by ourselves Alone (Pun intended

). A book does not interpret itself.
How many times did Jesus hit the Pharisees and Sadducees, etc over the head with Scriptures because they did not understand some Scripture passages correctly? Even more, the Devil dared to quote Scriptures when tempting Him in the dessert, and again, Jesus corrected him with Scriptures.
At first, it might seem that Scriptures can interpret itself. However, we are overlooking THE most important fact… Jesus was the one to interpret it. We see the example of the Eunuch; didn’t the HS take Phillip to him? Also, we don’t see anywhere in the Bible the Apostles receiving Bibles from Jesus. They were taught what Scriptures were truly about first.
If history has taught us anything is that, unless you interpret the Bible through Apostolic Tradition, you will have a mountain of misunderstanding running amok. Ironically enough, both Luther and Calvin were completely aware of that and did everything they could to avoid everyone interpreting Scriptures by themselves. As much as modern Protestantism likes to quote them both, NONE of them would agree with the protestant mess we have today. In fact, it is not about protesting anymore, it is all about a personal relationship with the Bible and believing that the Holy Spirit is guiding me to my own personal interpretation of Scriptures and completely ignorant of the fact of its history and responsibility!
Don’t take me wrong, I absolutely love the Bible. But I must love Truth as well, I can’t bend truth to fit my interpretation and expect to have a correct understanding of Scriptures.
Rant’s over…
I’d like to echo David’s post earlier: TGIF!!!