C
Conway97
Guest
I have a geneticist an endocrinologist and a urologist for my son who emphatically agree that it is not a hereditary disorder rather a miosis/ mitosis problem. 2002 data is rather old.In a 2002, Eskenazi, Wyrobek, Kidd, Lowe, More II, Weisiger, and Aylstock, research stated:“Inheritance of the extra X chromosome was paternal in 10 and maternal in 26 families. Fathers of paternal KS cases produced higher frequencies of XY sperm (P = 0.02) than fathers of maternal KS cases. After controlling for age, the major confounding variable, the difference between the two groups was no longer significant (P <= 0.2). Also there were no significant differences between the paternal origin groups for disomy X, Y, or 21. CONCLUSIONS: Men who fathered a child with a Klinefelter syndroms produced higher frequencies of XY sperm aneuploidy, which is explained in part, by both paternal age and parent of origin.”
Reference: Sperm aneuploidy in fathers of children with paternally and maternally inherited Klinefelter syndrome. Human Reproduction, Vol 17, No. 3, pp 576-583
Here is the nih info. ghr.nlm.nih.gov/condition/klinefelter-syndrome
I know this because my son has klinefelters and I live with it everyday and see doctors who specialize in it often