I’m not sure this precisely true – that rejection of the Apocrypha was the “exception” rather than the rule. The list of fathers who rejected the Apocrypha is long.
Many of the fathers agree that the Apocrypha is non-canonical and should not be included in the canon of inspired Scripture.
Melito of Sardis, (Eusebius – Lib. IV. Cap. 26.) testifies he knew the OT canon. He took great pains in research, as we are told by Eusebius, and comes to the exact number of books as the Protestants and Jews do.
Origen (Eus. Lib. VI c. 25) acknowledges the same books as the Protestants as canonical.
Athanasius says “Our whole scripture is divinely inspired and hath books not infinite in number, but finite and comprehended in a certain canon. The canonical books of the OT are two and twenty. Equal to the number as the Hebrew alphabet.”
Hilary, bishop of Poitiers, says, “The law of the OT is considered as divided into twenty-two books, so as to correspond to the number of letters.”
Nazianzen fixes the same number.
Cyril of Jerusalem, in his 4th catechetical discourse says much, “Do thou learn carefully from the church what are the books of the OT, Read the divine Scriptures, the two and twenty books. (Cyril. Hiersol. Catech. IV. 33. p. 67. ed Tuttei.)
**Epiphanius ** counts twenty seven, or by the Hebrew doubling, twenty two, “delivered by God to the Jews.” And he says of the apocryphal books, “They are indeed useful books, but are not included in the canon, and were not deposited in the ark of the covenant.”
Ruffinus, in his exposition of the Apostle’s Creed, says “But I should be known that there are other books also, which were called by the ancients not canonical but ecclesiastical, the Wisdom of Solomon and of Sirach, the book of Tobit, Judith, Macabees.
Jerome plainly rejects all the apocryphal books from the canon. “As there are twenty and two letters, so there are counted twenty and two books. Therefore the Wisdom of Solomon, and Jesus, and Judith, and Tobit, are not in the canon.” (See the introduction to the Vulgate in his own hand.)
“The church knows nothing of the apocryphal writings; we must therefore have recourse to the Hebrews, from whose text the Lord speaks, and his disciples chose their examples. What is not extant in them is to be flung away from us.” (Preface to Ezra and Nehemiah)
Jerome, in his preface to the books of Solomon, “As therefore the church, while it reads Judith and Tobit and the book of Maccabees, yet receives them not among the canonical Scriptures; so she may read these two volumes (Wisdom and Sirach) for the edification of the people, not for affirming the authority of faith.”
They are absurd who imagine a double canon. Jerome calls the Pelagians heretics (rightly so) for citing testimonies of the Apocrypha while attempting to prove something of heaven.
Gregory the Great, in his commentaries on Job, (Lib. XIX. Cap. 16.) expressly writes that the books of Macabees is not canonical, as well as the rest.
Josephus also agrees. In his first book against Apion the grammaritan “We have not innumerable books, inconsistent and conflicting with each other, but two and twenty books alone, containing the series of our whole history, and justly deemed worthy of our highest credit.” (Contra Apion. L. I. C. 8.)
Isidore, who lived in those times almost, (Lib. Isad. De Eccl. Offic. Lib. 1. c. 12.) says that the OT was settled by Ezra in two and twenty books, “that the books might correspond by the number of the letters.”
**John Damascus says (Lib. IV. C. 18) “It must be known that there are only two and twenty books of the OT, according to the alphabet of the Hebrew language.”
** Nicephorus, “There are two and twenty books of the OT.”
**Rabanus Maurus **(De. Institutes. Cler. C. 54) says that the whole OT was distributed by Ezra in two and twenty books, “that there may be as many in the law as in the letters.”
Radalphus (Lib. XIV. in Lev. c. 1.), “Tobit, Judith and the Macabees, although they be read for instruction in the church, yet have they not authority.”
Leotinus says in his book of Sects (act. 2.) that there are no more than twenty two canonical books as the churches receive.
**Hugo S. Victoris **(Prolog. Lib. I. De Sacram. C. 7.) says “that these books are read indeed, but not written in the body of the text or in the authoritative canon; that is, such as the book of Tobit, Judith, Macabees, the Wisdom of Solomon and Ecclesiasticus.”
**Richard de S. Victore **(Exception. Lib. II. C. 9), Lyra (prolog. In Libros Aprocryph.)
**Dionysius Carthusianus **(Comment in Gen. in Princip.) ,
Abulensis (in Matt. c. 1),
Antonius (3 p. Tit. XVIII. C. 5.),
**Cardinal Hugo (Prologue to Joshua) says the apocryphal books are not a rule for faith.
Cardinal Cajetan and ** Erasmus both declare the canon glossed by the apocryphal books being included in it in their time. (See Leo’s Epistle “Dilecto Filio Erasmo Roterd.”
Athanasius, who was the bishop of Alexandria where the LXX originated, rejected the Apocrypha. This is an important historical piece of supporting evidence that the LXX, at that time, did not include the Apocrypha. However, the evidence mounts as we continue to look into additional historical records.