If Adam and Eve had more starting diversity than four alleles at any one locus
From Sanford’s paper:
Together, these various genetic mechanisms seem to falsify the claim that there is “no way” that two people could give rise to the human allele distribution that we see today.
and
It seems to be the best explanation for how Adam and Eve might have simultaneously given rise to our current human allele patterns and our current linkage patterns.
In this paper we have used logic and numerical simulation to
show that there are several Designed Diversity mechanisms that
can reconcile a literal Adam and Eve with the allele frequency
distribution now seen in the human population. These genetic
mechanisms include: 1) designed diversity within Adam and
Eve’s four sets of chromosomes followed by accelerated genetic
drift associated with multiple population constrictions; 2) as
above, combined with more powerful demographic forces such
as selective sweeps, lineage extinctions, and differential sub-
population expansions; and 3) designed diversity within Adam
and Eve’s originally created gametogonia. Together, these various
genetic mechanisms seem to falsify the claim that there is “no way”
that two people could give rise to the human allele distribution that
we see today. The designed gametes model appears to be especially
robust, and in our opinion is even elegant. It seems to be the best
explanation for how Adam and Eve might have simultaneously
given rise to our current human allele patterns and our current
linkage patterns. Future research will examine the concept of
“demographic stirring” and how it may accelerate genetic drift.
Given the premise of a miraculously created Adam and Eve, the
most coherent, powerful, and compelling explanation for most of
the genetic diversity found within the human race is “designed
diversity”. This is especially true when we consider the various
forms of human beauty and the various forms of human gifts and
talents. Human traits of this type cannot rationally be attributed
to Darwinian mutation/selection. In addition, designed diversity
appears to have enabled rapid human adaptation after the flood.
http://creationicc.org/2018_papers/20 Sanford et al Adam and Eve final.pdf