I don’t think you’ll find too many Protestant who would deny that Jesus did as Mary asked. Protestants (and Catholics too me thinks) believe this is a great example of Jesus honoring the 5th Commandment. Protestants in general hold Mary in high regard, after all - she said “Yes” to God Almighty. Her selfless obedience is a model for all of us.
As to intercessory prayer, I would say that the average Protestant would refer directly to Romans 8:26:
“In the same way the Spirit also helps our weakness; for we do not know how to pray as we should, but the Spirit Himself intercedes for us with groanings too deep for words; 27 and He who searches the hearts knows what the mind of the Spirit is, because He intercedes for the saints according to the will of God.”
Praying to Mary - and to Saints - is a very…cultural thing I would say. I know you can make an argument for it Biblically, and I know Catholics are very comfortable with such prayer. I would just say that it makes many Protestants very uncomfortable. We’re just not “brought up” in the faith that way.
For example, I went to a Catholic Bible study one time and, as all Christians do, we opened with prayer. The leader said, “Let’s pray…Holy Mother…” and went on to pray a prayer. I know in my head that he was asking her to intercede for us. I know there is scriptural support for intercessory prayer to Saints (and all believers). I know that Catholics venerate Mary and don’t worship her. And yet…it was still very uncomfortable and awkward for me. This doesn’t mean I don’t respect my Catholic brothers and sisters for their beliefs - it just means its something that’s hard for me personally to experience.