The real issue is that genetic evolution alone has been found insufficient for an adequate causal explanation of all forms of phenotypic complexity, not only of something vaguely termed ‘macroevolution’.
I would say that the focus on what occurs at a molecular level, be it the structure of the genome or other related and necessary cellular processes, is “insufficient for an adequate causal explanation of all forms of phenotypic complexity”.
Everything that is happening here and now, centred around this communication happening through time and space, is composed of material substances. At the same time the chemical reactions occurring within neurons, as they form patterns of excitation in our brains, make no sense unless we consider the reality of the perceptions, thoughts, feelings and behavioural reactions that are taking place. That reality is psychological and rests on a spiritual foundation. We exist as relational beings, whole in ourselves and able to commune with one another and the Ground of our existence.
In a similar fashion, individual cats, dogs, elephants, hydrangeas, molds, and bacteria exist as themselves, expressions of a kind of living being. In their way, as we in ours, each type of existence represents a collection of relationships that transcends those of the organism’s molecular constituents, as it participates in the larger system that are its environment. The complexity of phenotypes has to do with the novel ways in which the individual creature relates to other members of its environment. The relationships that exit between the components that constitute the phenotype’s structure, described by chemistry and physics, are utilized in expressing the organism’s relational nature, but they do not account for it. This is what is brought into existence in the moment, and was created at some point in time, utilizing what had previously been brought into existence. Just as light and then atoms, had a beginning, so too did all creatures within the hierarchy of life, and ultimately ourselves, one mankind, united in love, broken in sin.