When that opposition takes the form of demonstrations and petitioning of one’s legislative representatives, you absolutely have a duty to “oppose” the government. God bless America as a place where we can do so. HOWEVER, when your “opposition” takes the form of an illegal act, the government must impose sanctions upon such individuals lest all our laws mean nothing.
This pharmacist’s religious freedom allowed him the right to refuse to fill the woman’s Rx. It did NOT allow him to deny her seeking it to be filled elsewhere. That act is tantamount to standing in the doorway to a sex ed class to prevent all the children from entering or patrolling the supermarket and pulling the bacon, ham, and pork chops from people’s shopping carts lest they eat of the unclean animal.
In short, you can practice your religion but you canNOT impose it upon others unless you want to open up a new branch of the Taliban.