Can you give me a real life scenario ?
Well, seeing extinctions of whole populations in areas where the habitat has been changed abruptly aren’t that hard to find. If you mean the actual data, here’s a paper that shows the sort of methods the biologists would use to find evidence for hypotheses about what could have caused extinctions at the end of the last Ice Age:
New research has revealed abrupt warming, that closely resembles the rapid man-made warming occurring today, has repeatedly played a key role in mass extinction events of large animals, the megafauna, in Earth's past.
www.sciencedaily.com
Likewise, you’re not going to see “real life” evidence of new species arising from nothing except in the fossil record. To the best of my knowledge, there has not been a single instance of a new species arising in the sense of a species with a totally different number of chromosomes, species that differ as much as, say, humans (with our 23 pairs of chromosomes) and apes and monkeys (with their 24 pairs.) Subspecies, yes, but not a new species with a different number of chromosomes, which obviously had to happen over and over again for evolution to take place on a grand scale.
There is evidence of such a possibility that can be had by comparing the human genome to that of other apes that our differerent number. Our genome is consistent with the change of a telomere-to-telemere fusion in an ancestor that had 24 pairs. To the best of my knowledge, though, there is no known mechanism by which this happens randomly. Certainly, if such a change happened to any of us, if it didn’t kill us it would still make us unable to be parents with anybody that had a genetic make-up that was typical before our mututation took place. That doesn’t mean such mechanisms don’t exist, but I really think there has to be a non-random attack on the DNA for that to happen to enough individuals to get a breeding population that come through the change with compatible genomes. There has to be more than random mutuations if evolution is the real origin of the species. There has to be non-random mechanisms that change a lot of organisms at once. It could be something that would kill 99% or even 99.9% of a population, provided it left a lot of individuals alive with a new genome that could interbreed with each other to propogate the drastically-changed genome.
Back to the topic of the thread, this shows why small “s” skepticism is fairly necessary if logic is going to be used to find the most likely explanations for physical phenomena. By small “s” skepticism, I mean not rushing to believe that what seems to be a really good explanation must be the correct explanation or that a better answer isn’t needed. That is in contrast to the OP’s example, which I’d call big “S” Skepticism: the conviction that there isn’t any way to know anything for sure no matter how much evidence you have for believing it.
As the singer Vicentico put it:
No creer en nada es creer en todo; that is: to believe in nothing is to believe in everything. There is some truth in that, I think. Well, big “s” Skepticism deserves to have its tires kicked, too. I think it really causes people to more gullible, not less gullible.